One of the oft repeated tips for a successful blog (so 2005) was that you should try to be consistent and stick to one topic. The thinking was that your readers would come to rely on you as a resource for your area of expertise, whether it was social media, knitting or fan girldom.
Well, that tip should be tossed out the window when you are using Twitter. While you can establish yourself as a great resource for a particular topic, the "best" Twitter users are those who take advantage of the medium to let their true personalities come out.
Sure, you're a marketing genius. But you're also a dad or a mom who likes Fraggle Rock and rides motorcycles and sings karaoke on the weekend — at least when you're not baking blueberry muffins, getting a new tattoo, remodeling the bathroom, traveling to yet another conference or client meeting or drawing cartoons on the back of business cards. You like Nick Cave or you drink too much scotch or you have an unhealthy obsession with Mad Men. You get angry, you get excited, you laugh at bad YouTube videos and you occasionally just need to put the blinders on and get some work done.
In other words, you're human, you're worth rooting for and you're worth tuning into to hear what happens next.